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Review of therapy response and survival of patients with glioma or glioblastoma and IDH mutation


Academic Paper, 2018

42 Pages, Grade: 85%


Excerpt


Contents

Introduction
Definition Gliomas and Glioblastomas
Isocitratdehydrogenase- Gene & the Enzyme IDH
Epidemiology and Prognosis
Cell of origin, Epigenetics & Genetic Pathways of Tumorigenesis
Treatment Implications of IDH
Indications for a Systematic Review

Aims

Methodology
Research Question
Databases
Search strategy
Study Selection
Eligibility criteria
Inclusion criteria
Exclusion criteria
Study Analysis/ Quality Assessment

Results
Search results
Study and participant characteristics

Analysis of Data & Discussion

Conclusion

References

Appendices
Appendix 1- the Search Strategy
Appendix 2- PRISMA flowchart
Appendix 3- Quality Assessment
A) Newcastle-Ottawa Scale
B) CASP-Tool
Appendix 4- Results-Table

Figures
Figure 1 — Diffuse Gliomas: from histology, IDH status and other genetic parameters
Figure 2 - Potential mechanism implicated in tumorigenesis induced by IDH MUTATION

Excerpt out of 42 pages

Details

Title
Review of therapy response and survival of patients with glioma or glioblastoma and IDH mutation
College
University of Southampton
Grade
85%
Author
Year
2018
Pages
42
Catalog Number
V465476
ISBN (eBook)
9783668934689
ISBN (Book)
9783668934696
Language
English
Keywords
review
Quote paper
Ronja Handwerker (Author), 2018, Review of therapy response and survival of patients with glioma or glioblastoma and IDH mutation, Munich, GRIN Verlag, https://www.grin.com/document/465476

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