Lupus Disease. Parthophysiology, Types, Symptoms and Medication

Elaboration 2018 8 Pages

Medicine - Epidemiology




Pathophysiology of Lupus

Types of Lupus

Symptoms of Lupus

Lupus Onset

Medication for Lupus




Lupus refers to an immune system’s disorder that is characterized with tissue swelling and severe pain. It occurs due to the inefficient determination of antibodies in the immune producing organs.

On the other hand, the lupus onset is usually non-specific in the view that it occurs among individuals in all races, sex and age. However, SLE is believed to be more prevalent among the old people than in the young ones.

Some of the most significant symptoms of lupus include skin rashes, joint pain and pleurisy, and treatment approaches focus on reducing the effects of these symptoms because lupus does not have a known cure at the moment. However, advancement in clinical research has led to the discovery of various pharmaceutical agents with potency against the lupus disease.


Lupus is an autoimmune disorder that affects various body parts such as the skin, brain, kidneys and other vital body organs, through causing inflammation in the affected region. In the scientific literature, lupus is defined by various names. Some of the most popular terms are systemic lupus erythematosus (SLE), lupus erythematosus and discoid lupus (Worsley, 2012). Ordinarily, lupus occurs when the immune system develops some genetic changes during the synthesis of antibodies, also referred to as lymphocytes. A recent research indicates that, the incidence rate of lupus within the global population is 5.6 per 100,000 people, in which women records a high incidence rate of 9.2 compared to 1.8 for men (Lim, 2014).

Pathophysiology of Lupus

Lupus disease occurs when an individual’s antibodies do not recognize ‘self antigens’ as ‘self.’ Instead, they recognize them as foreign; thus mounting an immune response towards them. As a result, useful body proteins are destroyed by the individual’s immune system, leading to the destruction of the respective body organs. The ultimate consequence is usually tissue pain, swelling and damage. Therefore, this paper will provide a comprehensive discussion on the lupus disease.

Types of Lupus

Lupus occurs in different forms, but the term lupus refers to the most popular form of lupus known as the systemic lupus erythematosus (SLE). Other forms of lupus include cutaneous (discoid) lupus, drug-induced lupus and neonatal lupus (Worsley, 2012). Systemic lupus erythematosus has been found to be the most prevalent of all forms of lupus, and it is not organ-specific. It is believed to affect virtually all body tissues, in which most patients experience inflammation of the joints, skin, lungs, the heart and the kidneys (Worsley, 2012).



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Title: Lupus Disease. Parthophysiology, Types, Symptoms and Medication