Evaluation of the Wound Healing Effect of Herbal Ointment Formulated with "Crateva Religiosa" Leaf Extract


Research Paper (postgraduate), 2013

5 Pages


Abstract or Introduction

The leaves of Crateva religiosa are used in traditional medicine for the treatment of various kinds of wounds. The present study was undertaken to evaluate the effect of herbal ointments formulated with the methanol extract of Crateva religiosa leaf on experimentally induced wounds in rats using the excision wound model. The animals were divided into five groups of five animals each. In the test groups 10, 15 and 20% extract of C. religiosa were topically applied once a day as ointment on groups 2, 3 and 4, respectively. Group 1 received blank petroleum jelly topically once a day while group 5 was treated topically with the standard drug, penicillin ointment. The mean wound sizes of all the animals were measured on the 3rd, 9th, 15th and 18th day post wounding and the mean percentage reduction in wound area calculated. Results obtained showed a dose dependent percentage reduction in wound area with the the 15% C. religiosa leaf extract (group 3) recording the highest mean percentage wound reduction (83 %) compared to the standard drug penicillin ointment which achieved complete wound healing after 18 days post wounding. This study suggests that C. religiosa leaf extract could be developed as a therapeutic agent for wound healing.

Details

Title
Evaluation of the Wound Healing Effect of Herbal Ointment Formulated with "Crateva Religiosa" Leaf Extract
College
Madonna University Elele, Nigeria
Course
Pharmaceutical and Medicinal Chemistry
Authors
Year
2013
Pages
5
Catalog Number
V207816
ISBN (eBook)
9783656367291
ISBN (Book)
9783656928683
File size
486 KB
Language
English
Keywords
evaluation, wound, healing, effect, herbal, ointment, formulated, crateva, religiosa, leaf, extract
Quote paper
Kingsley Adimabua (Author)G. A. Awemu (Author)C. A. Okonkwo (Author)A. M. Odiegwu (Author), 2013, Evaluation of the Wound Healing Effect of Herbal Ointment Formulated with "Crateva Religiosa" Leaf Extract, Munich, GRIN Verlag, https://www.grin.com/document/207816

Comments

  • No comments yet.
Look inside the ebook
Title: Evaluation of the Wound Healing Effect of Herbal Ointment Formulated with "Crateva Religiosa" Leaf Extract



Upload papers

Your term paper / thesis:

- Publication as eBook and book
- High royalties for the sales
- Completely free - with ISBN
- It only takes five minutes
- Every paper finds readers

Publish now - it's free