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Signal Validation can lead Vigilance
Just single ADRs relating the known benzene – toxicologic endpoints (leukemia, breast cancer) and these substances are worth to be investigated completely, since they enable risk assessments based on predisposition and epidemiology much earlier. The need of intelligence tools to deal with such heterogeneous data is obvious. The paradoxical situation that often arises is characterized by information overload but knowledge deficiency, and the need for intellectual involvement in information assimilation4. IT tools for intelligence are designed to assess risks in situations when only bits and pieces of knowledge are available but the situation forces to find the trace of future and past events (like it is the case in criminology, counter-terrorism, and military intelligence).
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- Ralf Arno Wess (Autor:in), 2005, Deductive, Systematic Signal Validation as Method for Efficacy Improvement in Pharmaco- and Chemo-Vigilance, München, GRIN Verlag, https://www.grin.com/document/125407
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